Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease
نویسندگان
چکیده
منابع مشابه
Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease ± the basic surface, at 2.0 AÊ resolution
A variant of bovine pancreatic ribonuclease A has been prepared with seven amino acid substitutions (Q55K, N62K, A64T, Y76K, S80R, E111G, N113K). These substitutions recreate in RNase A the basic surface found in bovine seminal RNase, a homologue of pancreatic RNase that diverged some 35 million years ago. Substitution of a portion of this basic surface (positions 55, 62, 64, 111 and 113) enhan...
متن کاملEffect of bovine seminal ribonuclease and bovine pancreatic ribonuclease A on bovine oocyte maturation.
Bovine seminal ribonuclease (BS-RNase) contains the MxM (noncovalent dimer) and M=M (free monomer) in constant ratio. The aim of this work was to evaluate the effect of BS-RNase, its monomer and dimer forms, and also various mutants of this enzyme on meiotic completion in cattle oocytes. It was found that BS-RNase has irreversible effects on the meiotic maturation of bovine oocytes in vitro, pa...
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هدف از انجام این تخقیق بررسی رابطه احتمالی بین سطح مهارت زبان خارجی (foreign language proficiency) و ساختار مهارت زبان خارجی بود. تعداد 314 زبان آموز مونث و مذکر که عمدتا دانشجویان رشته های زبان انگلیسی در سطوح کارشناسی و کارشناسی ارشد بودند در این تحقیق شرکت کردند. از لحاظ سطح مهارت زبان خارجی شرکت کنندگان بسیار با هم متفاوت بودند، (75 نفر سطح پیشرفته، 113 نفر سطح متوسط، 126 سطح مقدماتی). کلا ...
15 صفحه اولStructure and properties of seminal ribonuclease.
Brand, R. C. & Planta, R. J. (1975) Mol. Biol. Rep. 2, 321-325 Klootwijk, J. & Planta, R. J. (1973) Eur. J. Biochem. 39, 325-333 Maden, B. E. H. & Salim, M. (1974) J. Mol. Biol. 88, 133-164 Maden, B. E. H., Forbes, J., De Jonge, P. & Klootwijk, J. (1975) FEBSLerr. 59,60-63 Perry, R. P. (1976) Annu. Rev. Biochem. 45, 605-629 Planta, R. J., Van den Bos, R. C. & Klootwijk, J. (1972) in Ribosomes: ...
متن کاملStructural basis for the biological activities of bovine seminal ribonuclease.
Bovine seminal ribonuclease (BS-RNase) is a homolog of RNase A with special biological properties that include specific antitumor, aspermatogenic, and immuno-suppressive activities. Unlike RNase A, BS-RNase is a dimer cross-linked by disulfide bonds between Cys31 of one subunit and Cys32 of the other. At equilibrium, this dimer is a mixture of two distinct quaternary forms, M = M and M x M. The...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2003
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(03)01114-1